PT-141 (10mg), also known as bremelanotide, is a synthetic cyclic peptide studied for its effects on melanocortin receptor signaling in the central nervous system. Unlike compounds that act primarily on blood vessels, PT-141 is investigated for its effects on neurological pathways associated with sexual desire and arousal.

Bremelanotide is the active ingredient in an FDA-approved prescription medication for a specific indication in premenopausal women. Research involving other populations, uses, and formulations remains distinct from that approved use.

Mechanism of Action

PT-141 interacts with melanocortin receptors, particularly MC3R and MC4R, which are involved in several physiological and neurological processes.

• Melanocortin Receptor Activation: PT-141 activates melanocortin receptors involved in central nervous system signaling.

• Central Nervous System Pathways: Research investigates how melanocortin signaling influences sexual motivation, desire, and arousal.

• Neurological Signaling: Studies examine interactions between melanocortin pathways and neural circuits involved in behavioral and physiological responses.

• Distinct From Direct Vasodilators: PT-141's proposed effects differ from those of medications that primarily increase blood flow through vascular mechanisms.

Research Area

• Sexual Desire & Arousal: Investigation of melanocortin signaling pathways associated with sexual motivation and arousal.

• Central Nervous System Research: Study of the relationship between melanocortin receptor activation and neurological responses.

• Melanocortin Biology: Exploration of MC3R and MC4R signaling and their physiological roles.

• Clinical Pharmacology: Research into the pharmacological effects, tolerability, and safety profile of bremelanotide.

Technical Specifications

• Product Name: PT-141

• Common Name: Bremelanotide

• Labeled Quantity: 10mg

• Compound Type: Synthetic cyclic peptide

• Primary Research Target: Melanocortin receptor signaling

Research Use Only: This research product is not approved for human or veterinary use.